BDBM217352 GS-9820

SMILES C[C@H](Nc1ncnc2[nH]cnc12)c1nc2ccc(F)cc2c(=O)n1-c1ccccc1

InChI Key

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 217352   

LigandPNGBDBM217352(GS-9820)
Affinity DataIC50:  5.44E+3nMAssay Description:Biochemical in vitro lipid kinase assays were performed by the SelectScreenŽ biochemical kinase assay service (Invitrogen Ltd.). A stock solution of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM217352(GS-9820)
Affinity DataIC50:  3.38E+3nMAssay Description:Biochemical in vitro lipid kinase assays were performed by the SelectScreenŽ biochemical kinase assay service (Invitrogen Ltd.). A stock solution of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM217352(GS-9820)
Affinity DataIC50:  1.39E+3nMAssay Description:Biochemical in vitro lipid kinase assays were performed by the SelectScreenŽ biochemical kinase assay service (Invitrogen Ltd.). A stock solution of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM217352(GS-9820)
Affinity DataIC50:  12.7nMAssay Description:Biochemical in vitro lipid kinase assays were performed by the SelectScreenŽ biochemical kinase assay service (Invitrogen Ltd.). A stock solution of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-phosphate 5-kinase type-1 alpha(Mus musculus (Mouse))
Western University

LigandPNGBDBM217352(GS-9820)
Affinity DataIC50: >1.00E+4nMAssay Description:Biochemical in vitro lipid kinase assays were performed by the SelectScreenŽ biochemical kinase assay service (Invitrogen Ltd.). A stock solution of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM217352(GS-9820)
Affinity DataIC50:  13nMAssay Description:Inhibition of PI3K-delta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Mus musculus (Mouse))
Western University

LigandPNGBDBM217352(GS-9820)
Affinity DataIC50:  1.87E+4nMAssay Description:Biochemical in vitro lipid kinase assays were performed by the SelectScreenŽ biochemical kinase assay service (Invitrogen Ltd.). A stock solution of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Mus musculus (Mouse))
Western University

LigandPNGBDBM217352(GS-9820)
Affinity DataIC50: >1.00E+5nMAssay Description:Biochemical in vitro lipid kinase assays were performed by the SelectScreenŽ biochemical kinase assay service (Invitrogen Ltd.). A stock solution of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM217352(GS-9820)
Affinity DataIC50:  13nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM217352(GS-9820)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of GST-tagged PI3Kgamma (unknown origin) using PIP2 as substrate preincubated for 2 hrs followed by ATP addition measured after 30 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM217352(GS-9820)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-phosphate 5-kinase type-1 beta(Mus musculus (Mouse))
Western University

LigandPNGBDBM217352(GS-9820)
Affinity DataIC50: >1.00E+4nMAssay Description:Biochemical in vitro lipid kinase assays were performed by the SelectScreenŽ biochemical kinase assay service (Invitrogen Ltd.). A stock solution of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed