BDBM217378 (S)-6-hydroxynicotine::5-[(2S)-1-methylpyrrolidin-2-yl]-1H-pyridin-2-one

SMILES CN1CCC[C@H]1c1ccc(=O)[nH]c1

InChI Key InChIKey=ATRCOGLZUCICIV-VIFPVBQESA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 217378   

Target(S)-6-hydroxynicotine oxidase [N166A](Arthrobacter nicotinovorans)
University of Texas Health Science Center

LigandPNGBDBM217378((S)-6-hydroxynicotine | 5-[(2S)-1-methylpyrrolidin...)
Affinity DataKd:  3.10E+5nMpH: 8.0 T: 2°CAssay Description:Initial rates of amine oxidation were measured by monitoring oxygen consumption using an oxygen electrode (model 5300A, Yellow Springs Instruments, Y...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target(S)-6-hydroxynicotine oxidase [Y311F](Arthrobacter nicotinovorans)
University of Texas Health Science Center

LigandPNGBDBM217378((S)-6-hydroxynicotine | 5-[(2S)-1-methylpyrrolidin...)
Affinity DataKd:  9.60E+4nMpH: 8.0 T: 2°CAssay Description:Initial rates of amine oxidation were measured by monitoring oxygen consumption using an oxygen electrode (model 5300A, Yellow Springs Instruments, Y...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target(S)-6-hydroxynicotine oxidase [K287M](Arthrobacter nicotinovorans)
University of Texas Health Science Center

LigandPNGBDBM217378((S)-6-hydroxynicotine | 5-[(2S)-1-methylpyrrolidin...)
Affinity DataKd:  6.10E+4nMpH: 8.0 T: 2°CAssay Description:Initial rates of amine oxidation were measured by monitoring oxygen consumption using an oxygen electrode (model 5300A, Yellow Springs Instruments, Y...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed