BDBM217435 US9212182, 323::US9212182, 324
SMILES COc1cc(ccc1-n1c2ccc(cc2ccc1=O)S(=O)(=O)Nc1ccon1)-c1cccc(c1)C(F)(F)F
InChI Key InChIKey=SFRPLFSOLCJRQZ-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 217435
Affinity DataIC50: 23nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Affinity DataIC50: 4.48E+3nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Binding affinity towards estrogen receptor beta by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Reversible inhibition of CYP3A4 in human liver microsomes using midazolam as substrate in presence of NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Ability to activate estrogen receptor 2-mediated transcription.More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+4nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated with enzyme in presence of NADPH followed by ...More data for this Ligand-Target Pair