BDBM21787 2-[(1S)-5-{3-[2-methoxy-4-(1,3-thiazol-2-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid::Indanylacetic Acid Analog, 34b

SMILES COc1cc(ccc1OCCCOc1ccc2[C@H](CC(O)=O)CCc2c1)-c1nccs1

InChI Key InChIKey=YKDMIPMJDYHYSQ-KRWDZBQOSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 21787   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21787(2-[(1S)-5-{3-[2-methoxy-4-(1,3-thiazol-2-yl)phenox...)
Affinity DataEC50:  255nMT: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21787(2-[(1S)-5-{3-[2-methoxy-4-(1,3-thiazol-2-yl)phenox...)
Affinity DataEC50:  0.580nMT: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21787(2-[(1S)-5-{3-[2-methoxy-4-(1,3-thiazol-2-yl)phenox...)
Affinity DataEC50:  5.80E+8nMAssay Description:Agonist activity at GST-tagged Homo sapiens (human) PPARdelta ligand binding domain after 2 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21787(2-[(1S)-5-{3-[2-methoxy-4-(1,3-thiazol-2-yl)phenox...)
Affinity DataEC50:  3.92E+6nMAssay Description:Agonist activity at GST-tagged Homo sapiens (human) PPARalpha ligand binding domain after 2 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM21787(2-[(1S)-5-{3-[2-methoxy-4-(1,3-thiazol-2-yl)phenox...)
Affinity DataEC50:  2.69E+6nMAssay Description:Agonist activity at Homo sapiens (human) PPARgamma expressed in mouse 3T3-L1 cells incubated for 2 days followed by compound wash out measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM21787(2-[(1S)-5-{3-[2-methoxy-4-(1,3-thiazol-2-yl)phenox...)
Affinity DataEC50:  374nMT: 2°CAssay Description:PPAR gamma activity was assessed by using the IRBA in mouse 3T3-L1 cells. This assay measures the ability of test compound to cause an increase in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed