BDBM217889 US9212182, 632
SMILES COc1cc(c(F)cc1-n1c2ccc(cc2ccc1=O)S(=O)(=O)Nc1ccon1)-c1cccc(OC(F)F)c1
InChI Key InChIKey=ANRNNOYJCDFVSP-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 217889
Affinity DataIC50: 9nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated with enzyme in presence of NADPH followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Binding affinity towards estrogen receptor beta by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Ability to activate estrogen receptor 1-mediated transcription.More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Binding affinity towards estrogen receptor alpha by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair