BDBM218224 US9249087, Table 1 , Compound 1

SMILES ONC(=O)c1ccc(cc1)-c1ccc2ccccc12

InChI Key

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 218224   

TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218224(US9249087, Table 1 , Compound 1)
Affinity DataIC50:  5.83E+3nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218224(US9249087, Table 1 , Compound 1)
Affinity DataIC50:  9.19E+3nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218224(US9249087, Table 1 , Compound 1)
Affinity DataIC50:  8.16E+3nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218224(US9249087, Table 1 , Compound 1)
Affinity DataIC50:  417nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218224(US9249087, Table 1 , Compound 1)
Affinity DataIC50:  9.75nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent