BDBM218226 US9249087, Table 1 , Compound 3

SMILES Cc1cc(-c2ccc(cc2)C(=O)NO)c2ccccc12

InChI Key InChIKey=KKGXKTBUHWBYBN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 218226   

TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218226(US9249087, Table 1 , Compound 3)
Affinity DataIC50:  6.79E+3nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218226(US9249087, Table 1 , Compound 3)
Affinity DataIC50:  1.19E+4nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218226(US9249087, Table 1 , Compound 3)
Affinity DataIC50:  1.45E+4nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218226(US9249087, Table 1 , Compound 3)
Affinity DataIC50:  911nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois

US Patent
LigandPNGBDBM218226(US9249087, Table 1 , Compound 3)
Affinity DataIC50:  5.11nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent