BDBM218855 US9303033, F39, Table 43A, Compound 9::US9303033, M1, Table 4A, Compound 7

SMILES CC(C)Oc1cccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1

InChI Key InChIKey=MWRXPVUOFUGJNR-IUXPMGMMSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 218855   

TargetCasein kinase II subunit alpha/beta(Homo sapiens (Human))
Senhwa Biosciences

US Patent
LigandPNGBDBM218855(US9303033, F39, Table 43A, Compound 9 | US9303033,...)
Affinity DataIC50: <10nMpH: 7.2Assay Description:In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase II subunit alpha/beta(Homo sapiens (Human))
Senhwa Biosciences

US Patent
LigandPNGBDBM218855(US9303033, F39, Table 43A, Compound 9 | US9303033,...)
Affinity DataIC50: <10nMpH: 7.2Assay Description:In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase II subunit beta(Homo sapiens (Human))
Senhwa Biosciences

US Patent
LigandPNGBDBM218855(US9303033, F39, Table 43A, Compound 9 | US9303033,...)
Affinity DataIC50: >2.50E+3nMpH: 7.0Assay Description:5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent