BDBM221448 US9303025, 138

SMILES CN(C)CCCNc1ccc(NC(=O)c2ccc(cc2Oc2cccc(F)c2)N2CCN(CC3=C(CC(C)(C)CC3)c3ccc(Cl)cc3)CC2)cc1[N+]([O-])=O

InChI Key InChIKey=GLRTXOSJRDRRIJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 221448   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM221448(US9303025, 138)
Affinity DataKi:  0.0160nM ΔG°:  -14.7kcal/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent