BDBM22188 1-(4-{2-[bis(4-fluorophenyl)methoxy]ethyl}piperazin-1-yl)-3-phenylpropan-2-one::GBR 12935 Analogue, 17

SMILES Fc1ccc(cc1)C(OCCN1CCN(CC(=O)Cc2ccccc2)CC1)c1ccc(F)cc1

InChI Key InChIKey=JJFAOKMTNYBVNH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22188   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Taiwan University

LigandPNGBDBM22188(1-(4-{2-[bis(4-fluorophenyl)methoxy]ethyl}piperazi...)
Affinity DataKi:  6.5nMAssay Description:The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Taiwan University

LigandPNGBDBM22188(1-(4-{2-[bis(4-fluorophenyl)methoxy]ethyl}piperazi...)
Affinity DataKi:  250nMAssay Description:The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed