BDBM221902 US9315463, 12
SMILES COc1cc(NC(=O)OCCN(C)[C@H]2CC[C@@H](CC2)OC(=O)C(O)(c2cccs2)c2cccs2)c(Cl)cc1CNC[C@H](O)c1ccc(O)c2[nH]c(=O)ccc12
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 221902
Affinity DataIC50: 1.60nMT: 2°CAssay Description:The study of binding to human adrenergic beta1 and beta2 receptors was performed using commercial membranes prepared from Sf9 cells where they are ov...More data for this Ligand-Target Pair
Affinity DataEC50: 0.251nMAssay Description:Agonist activity at human beta2 adrenoceptorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
School Of Pharmaceutical Sciences & The Fifth Affiliated Hospital
Curated by ChEMBL
School Of Pharmaceutical Sciences & The Fifth Affiliated Hospital
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human M3 receptorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
School Of Pharmaceutical Sciences & The Fifth Affiliated Hospital
Curated by ChEMBL
School Of Pharmaceutical Sciences & The Fifth Affiliated Hospital
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:The study of binding to human muscarinic M1, M2, M3, M4 and M5 receptors was performed using commercial membranes (Perkin Elmer) prepared from CHO-K1...More data for this Ligand-Target Pair