BDBM222092 6-(4-Methanesulfonylaminophenyl)-2-oxo-4-(4-tolyl)-1,2-dihydropyridine-3-carbonitrile (4n)

SMILES Cc1ccc(cc1)-c1cc([nH]c(=O)c1C#N)-c1ccc(NS(C)(=O)=O)cc1

InChI Key InChIKey=OHAZAMMTOXHBGM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222092   

TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Fayoum University

LigandPNGBDBM222092(6-(4-Methanesulfonylaminophenyl)-2-oxo-4-(4-tolyl)...)
Affinity DataIC50:  1.30E+3nMAssay Description:The ability of the tested compounds to inhibit both isozymes, COX-1 and COX-2 was measured using colorimetric COX (ovine) Inhibitor Screening Assay K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Fayoum University

LigandPNGBDBM222092(6-(4-Methanesulfonylaminophenyl)-2-oxo-4-(4-tolyl)...)
Affinity DataIC50:  8.60E+3nMAssay Description:The ability of the tested compounds to inhibit both isozymes, COX-1 and COX-2 was measured using colorimetric COX (ovine) Inhibitor Screening Assay K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed