BDBM222239 N3-(3-Nitrobenzylidene)-2-phenyl-N4-(thiazol-2-yl)-quinazoline-3,4-(4H)-diamine (7b)

SMILES [O-][N+](=O)c1cccc(\C=N\N2C(Nc3nccs3)c3ccccc3N=C2c2ccccc2)c1

InChI Key InChIKey=UKDYAWHJWKZVGF-WGOQTCKBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222239   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM222239(N3-(3-Nitrobenzylidene)-2-phenyl-N4-(thiazol-2-yl)...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of DPP4 (unknown origin) using H-Gly-Pro-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM222239(N3-(3-Nitrobenzylidene)-2-phenyl-N4-(thiazol-2-yl)...)
Affinity DataIC50:  1.33nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed