BDBM222254 6-Iodo-N4-(4-methylthiazol-2-yl)-N3-(3-nitrobenzylidene)-2-phenylquinazoline-3,4-(4H)diamine (8g)

SMILES Cc1csc(NC2N(\N=C\c3cccc(c3)[N+]([O-])=O)C(=Nc3ccc(I)cc23)c2ccccc2)n1

InChI Key InChIKey=XGZAFAPLBQLTIJ-MZJWZYIUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222254   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM222254(6-Iodo-N4-(4-methylthiazol-2-yl)-N3-(3-nitrobenzyl...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of DPP4 (unknown origin) using H-Gly-Pro-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM222254(6-Iodo-N4-(4-methylthiazol-2-yl)-N3-(3-nitrobenzyl...)
Affinity DataIC50:  1.22nMAssay Description:The synthetic title compounds 7 (a-j) and 8 (a-j) were screened for in vitro DPP-4 inhibition using DPP-4 activity assay kit (Krishgen BioSystems). D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed