BDBM222262 (Z)-4-(2-((E)-4-(3,4-dimethoxyphenyl)-1-morpholino-2-oxobut-3-enylidene) hydrazinyl) benzenesulfonamide (4e)

SMILES COc1ccc(\C=C\C(=O)C(=N\Nc2ccc(cc2)S(N)(=O)=O)\N2CCOCC2)cc1OC

InChI Key InChIKey=IZCANRPFPVWXMP-JGGPRTMHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 222262   

Target5'-nucleotidase(Homo sapiens (Human))
Comsats Institute of Information Technology

LigandPNGBDBM222262((Z)-4-(2-((E)-4-(3,4-dimethoxyphenyl)-1-morpholino...)
Affinity DataIC50:  260nMpH: 7.4 T: 2°CAssay Description:The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Bos taurus (Cattle))
Comsats Institute of Information Technology

LigandPNGBDBM222262((Z)-4-(2-((E)-4-(3,4-dimethoxyphenyl)-1-morpholino...)
Affinity DataIC50:  350nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute of Information Technology

LigandPNGBDBM222262((Z)-4-(2-((E)-4-(3,4-dimethoxyphenyl)-1-morpholino...)
Affinity DataIC50:  7.41E+3nMpH: 7.4 T: 2°CAssay Description:The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed