BDBM222266 (Z)-4-(2-((E)-4-(2-bromophenyl)-1-morpholino-2-oxobut-3-enylidene)hydrazinyl) benzenesulfonamide (4i)

SMILES NS(=O)(=O)c1ccc(N\N=C(/N2CCOCC2)C(=O)\C=C\c2ccccc2Br)cc1

InChI Key InChIKey=IXAXMBLJNOJYEA-RSJLAWTDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 222266   

Target5'-nucleotidase(Homo sapiens (Human))
Comsats Institute of Information Technology

LigandPNGBDBM222266((Z)-4-(2-((E)-4-(2-bromophenyl)-1-morpholino-2-oxo...)
Affinity DataIC50:  2.92E+3nMpH: 7.4 T: 2°CAssay Description:The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Bos taurus (Cattle))
Comsats Institute of Information Technology

LigandPNGBDBM222266((Z)-4-(2-((E)-4-(2-bromophenyl)-1-morpholino-2-oxo...)
Affinity DataIC50:  1.21E+3nMpH: 9.8 T: 2°CAssay Description:Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Comsats Institute of Information Technology

LigandPNGBDBM222266((Z)-4-(2-((E)-4-(2-bromophenyl)-1-morpholino-2-oxo...)
Affinity DataIC50:  2.24E+4nMpH: 7.4 T: 2°CAssay Description:The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed