BDBM222458 (E)-4-[2-(4-Chlorophenyl)-5-oxo-4-(4-trifluoromethylbenzylidene)-4,5-dihydroimidazol-1-yl]-benzenesulfonamide (10b)

SMILES NS(=O)(=O)c1ccc(cc1)N1C(=O)\C(=C/c2ccc(cc2)C(F)(F)F)N=C1c1ccc(Cl)cc1

InChI Key InChIKey=UONWOZTYKSPEHN-DEDYPNTBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222458   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Beni-Suef University

LigandPNGBDBM222458((E)-4-[2-(4-Chlorophenyl)-5-oxo-4-(4-trifluorometh...)
Affinity DataIC50:  620nMAssay Description:The ability of the test compounds 10a-h listed in Table 1 to inhibit ovine COX-1 and human recombinant COX-2 (IC50 value, mM) was determined using an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Beni-Suef University

LigandPNGBDBM222458((E)-4-[2-(4-Chlorophenyl)-5-oxo-4-(4-trifluorometh...)
Affinity DataIC50:  6.74E+3nMAssay Description:The ability of the test compounds 10a-h listed in Table 1 to inhibit ovine COX-1 and human recombinant COX-2 (IC50 value, mM) was determined using an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed