BDBM222460 (E)-4-[2-(4-Chlorophenyl)-4-(3,4-dimethoxybenzylidene)-5-oxo-4,5-dihydroimidazol-1-yl]-benzenesulfonamide (10d)

SMILES COc1ccc(\C=C2\N=C(N(C2=O)c2ccc(cc2)S(N)(=O)=O)c2ccc(Cl)cc2)cc1OC

InChI Key InChIKey=BNXCBMFAJMMUKV-DEDYPNTBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222460   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Beni-Suef University

LigandPNGBDBM222460((E)-4-[2-(4-Chlorophenyl)-4-(3,4-dimethoxybenzylid...)
Affinity DataIC50:  550nMAssay Description:The ability of the test compounds 10a-h listed in Table 1 to inhibit ovine COX-1 and human recombinant COX-2 (IC50 value, mM) was determined using an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Beni-Suef University

LigandPNGBDBM222460((E)-4-[2-(4-Chlorophenyl)-4-(3,4-dimethoxybenzylid...)
Affinity DataIC50:  3.85E+3nMAssay Description:The ability of the test compounds 10a-h listed in Table 1 to inhibit ovine COX-1 and human recombinant COX-2 (IC50 value, mM) was determined using an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed