BDBM222462 (E)-4-[4-(2-Chlorobenzylidene)-2-(4-chlorophenyl)-5-oxo-4,5-dihydroimidazol-1-yl]-benzene-sulfonamide (10f)
SMILES NS(=O)(=O)c1ccc(cc1)N1C(=O)\C(=C/c2ccccc2Cl)N=C1c1ccc(Cl)cc1
InChI Key InChIKey=VWRFFXRMUHACGT-DEDYPNTBSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 222462
Affinity DataIC50: 7.86E+3nMAssay Description:The ability of the test compounds 10a-h listed in Table 1 to inhibit ovine COX-1 and human recombinant COX-2 (IC50 value, mM) was determined using an...More data for this Ligand-Target Pair
Affinity DataIC50: 7.86E+3nMAssay Description:Inhibition of ovine COX1 by EIAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Wuhan University Of Technology
Curated by ChEMBL
Wuhan University Of Technology
Curated by ChEMBL
Affinity DataIC50: 860nMAssay Description:Inhibition of recombinant human COX2 by EIAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Wuhan University Of Technology
Curated by ChEMBL
Wuhan University Of Technology
Curated by ChEMBL
Affinity DataIC50: 860nMAssay Description:The ability of the test compounds 10a-h listed in Table 1 to inhibit ovine COX-1 and human recombinant COX-2 (IC50 value, mM) was determined using an...More data for this Ligand-Target Pair