BDBM222462 (E)-4-[4-(2-Chlorobenzylidene)-2-(4-chlorophenyl)-5-oxo-4,5-dihydroimidazol-1-yl]-benzene-sulfonamide (10f)

SMILES NS(=O)(=O)c1ccc(cc1)N1C(=O)\C(=C/c2ccccc2Cl)N=C1c1ccc(Cl)cc1

InChI Key InChIKey=VWRFFXRMUHACGT-DEDYPNTBSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 222462   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Beni-Suef University

LigandPNGBDBM222462((E)-4-[4-(2-Chlorobenzylidene)-2-(4-chlorophenyl)-...)
Affinity DataIC50:  7.86E+3nMAssay Description:The ability of the test compounds 10a-h listed in Table 1 to inhibit ovine COX-1 and human recombinant COX-2 (IC50 value, mM) was determined using an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Beni-Suef University

LigandPNGBDBM222462((E)-4-[4-(2-Chlorobenzylidene)-2-(4-chlorophenyl)-...)
Affinity DataIC50:  7.86E+3nMAssay Description:Inhibition of ovine COX1 by EIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Wuhan University Of Technology

Curated by ChEMBL
LigandPNGBDBM222462((E)-4-[4-(2-Chlorobenzylidene)-2-(4-chlorophenyl)-...)
Affinity DataIC50:  860nMAssay Description:Inhibition of recombinant human COX2 by EIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Wuhan University Of Technology

Curated by ChEMBL
LigandPNGBDBM222462((E)-4-[4-(2-Chlorobenzylidene)-2-(4-chlorophenyl)-...)
Affinity DataIC50:  860nMAssay Description:The ability of the test compounds 10a-h listed in Table 1 to inhibit ovine COX-1 and human recombinant COX-2 (IC50 value, mM) was determined using an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed