BDBM22291 N-{2-[2-(4-methoxyphenyl)-1H-indol-3-yl]ethyl}-4-methylbenzene-1-sulfonamide::tryptamine sulfonamide, 37a

SMILES COc1ccc(cc1)-c1[nH]c2ccccc2c1CCNS(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=WIWFZAFGANEVLX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22291   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
Bristol-Myers Squibb

LigandPNGBDBM22291(N-{2-[2-(4-methoxyphenyl)-1H-indol-3-yl]ethyl}-4-m...)
Affinity DataIC50:  110nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed