BDBM222990 US9315518, 34-3
SMILES CC1C(C1C(C)(C)O)c1ccc2N(CC3CC3(F)F)S(=O)(=O)N(C)c2n1
InChI Key InChIKey=XKZJGPAQRAEUDQ-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 222990
Affinity DataEC50: 40.6nMAssay Description:The stimulation of [35S]-GTPγS binding is a common functional assay to monitor Gαi-coupled receptor in native and recombinant receptor memb...More data for this Ligand-Target Pair
TargetGuanine nucleotide-binding protein subunit alpha-15 [Y147C]/Metabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataEC50: 14.4nMAssay Description:The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...More data for this Ligand-Target Pair