BDBM223076 (E)-N'-(3'-Nitrobenzylidene)isonicotinohydrazide (3f)

SMILES [O-][N+](=O)c1cccc(\C=N\NC(=O)c2ccncc2)c1

InChI Key InChIKey=GTORRVVNCWSJKS-OQLLNIDSSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 223076   

Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM223076((E)-N'-(3'-Nitrobenzylidene)isonicotinohyd...)
Affinity DataIC50:  1.90E+3nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Quaid-I-Azam University

LigandPNGBDBM223076((E)-N'-(3'-Nitrobenzylidene)isonicotinohyd...)
Affinity DataIC50:  210nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM223076((E)-N'-(3'-Nitrobenzylidene)isonicotinohyd...)
Affinity DataIC50:  1.74E+5nMAssay Description:Inhibition of bovine xanthine oxidase using xanthine as substrate preincubated for 10 mins followed by substrate addition measured for 15 mins by spe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Bos taurus (Cattle))
Quaid-I-Azam University

LigandPNGBDBM223076((E)-N'-(3'-Nitrobenzylidene)isonicotinohyd...)
Affinity DataIC50:  7.34E+3nMpH: 9.8 T: 2°CAssay Description:The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bos taurus (Cattle))
Quaid-I-Azam University

LigandPNGBDBM223076((E)-N'-(3'-Nitrobenzylidene)isonicotinohyd...)
Affinity DataIC50:  1.82E+3nMpH: 9.8 T: 2°CAssay Description:The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed