BDBM223077 (E)-N'-(4'-Hydroxy-3-methoxybenzylidene)isonicotinohydrazide (3g)

SMILES COc1cc(\C=N\NC(=O)c2ccncc2)ccc1O

InChI Key InChIKey=PSWOBQSIXLVPDV-CXUHLZMHSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 223077   

Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM223077((E)-N'-(4'-Hydroxy-3-methoxybenzylidene)is...)
Affinity DataIC50:  680nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Quaid-I-Azam University

LigandPNGBDBM223077((E)-N'-(4'-Hydroxy-3-methoxybenzylidene)is...)
Affinity DataIC50:  140nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM223077((E)-N'-(4'-Hydroxy-3-methoxybenzylidene)is...)
Affinity DataIC50:  460nMAssay Description:Inhibition of human MPOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Bos taurus (Cattle))
Quaid-I-Azam University

LigandPNGBDBM223077((E)-N'-(4'-Hydroxy-3-methoxybenzylidene)is...)
Affinity DataIC50:  1.92E+3nMpH: 9.8 T: 2°CAssay Description:The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bos taurus (Cattle))
Quaid-I-Azam University

LigandPNGBDBM223077((E)-N'-(4'-Hydroxy-3-methoxybenzylidene)is...)
Affinity DataIC50:  350nMpH: 9.8 T: 2°CAssay Description:The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed