BDBM223079 (E)-N'-(Pyridin-3'-ylmethylene)isonicotinohydrazide (3i)

SMILES O=C(N\N=C\c1cccnc1)c1ccncc1

InChI Key InChIKey=DERMXJNBYDETST-OQLLNIDSSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 223079   

Target5'-nucleotidase(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM223079((E)-N'-(Pyridin-3'-ylmethylene)isonicotino...)
Affinity DataIC50:  210nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Bos taurus (Cattle))
Quaid-I-Azam University

LigandPNGBDBM223079((E)-N'-(Pyridin-3'-ylmethylene)isonicotino...)
Affinity DataIC50:  1.46E+3nMpH: 9.8 T: 2°CAssay Description:The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bos taurus (Cattle))
Quaid-I-Azam University

LigandPNGBDBM223079((E)-N'-(Pyridin-3'-ylmethylene)isonicotino...)
Affinity DataIC50:  2.43E+3nMpH: 9.8 T: 2°CAssay Description:The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))
Quaid-I-Azam University

LigandPNGBDBM223079((E)-N'-(Pyridin-3'-ylmethylene)isonicotino...)
Affinity DataIC50:  3.01E+3nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed