BDBM22317 4-({2-[2-(1-benzofuran-2-yl)-1H-indol-3-yl]ethyl}sulfamoyl)-N-[2-(dimethylamino)ethyl]-N-methylbenzamide::tryptamine sulfonamide, 40j

SMILES CN(C)CCN(C)C(=O)c1ccc(cc1)S(=O)(=O)NCCc1c([nH]c2ccccc12)-c1cc2ccccc2o1

InChI Key InChIKey=NCQIGJNVOCUQKG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22317   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
Bristol-Myers Squibb

LigandPNGBDBM22317(4-({2-[2-(1-benzofuran-2-yl)-1H-indol-3-yl]ethyl}s...)
Affinity DataIC50:  76nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed