BDBM22352 1,3-Diarylprop-2-yn-1-one, 13i::1-(3,4-difluorophenyl)-3-(4-methanesulfonylphenyl)prop-2-yn-1-one::CHEMBL197573
SMILES CS(=O)(=O)c1ccc(cc1)C#CC(=O)c1ccc(F)c(F)c1
InChI Key InChIKey=ZYQKSSGGSWACEA-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 22352
Affinity DataIC50: 3.10E+3nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:The lipoxygenase inhibitor screening assay detects and measures the hydroperoxides produced in the lipoxygenation reaction using a purified lipoxygen...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:In vitro inhibitory activity against ovine cyclooxygenase 1More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:In vitro inhibitory activity against ovine cyclooxygenase 2More data for this Ligand-Target Pair
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:In vitro inhibitory activity against 15-lipoxygenase obtained from soybeanMore data for this Ligand-Target Pair
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase obtained from potatoMore data for this Ligand-Target Pair
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of Alberta
Curated by ChEMBL
University Of Alberta
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:The lipoxygenase inhibitor screening assay detects and measures the hydroperoxides produced in the lipoxygenation reaction using a purified lipoxygen...More data for this Ligand-Target Pair