BDBM22359 1,3-Diarylprop-2-yn-1-one, 13p::methyl 4-[3-(4-methanesulfonylphenyl)prop-2-ynoyl]benzoate

SMILES COC(=O)c1ccc(cc1)C(=O)C#Cc1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=LSHKKTLXXOBXIY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22359   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University of Alberta

LigandPNGBDBM22359(1,3-Diarylprop-2-yn-1-one, 13p | methyl 4-[3-(4-me...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University of Alberta

LigandPNGBDBM22359(1,3-Diarylprop-2-yn-1-one, 13p | methyl 4-[3-(4-me...)
Affinity DataIC50:  5.00E+3nMAssay Description:The lipoxygenase inhibitor screening assay detects and measures the hydroperoxides produced in the lipoxygenation reaction using a purified lipoxygen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoxygenase(Solanum tuberosum (potato))
University of Alberta

LigandPNGBDBM22359(1,3-Diarylprop-2-yn-1-one, 13p | methyl 4-[3-(4-me...)
Affinity DataIC50: >1.00E+4nMAssay Description:The lipoxygenase inhibitor screening assay detects and measures the hydroperoxides produced in the lipoxygenation reaction using a purified lipoxygen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Alberta

LigandPNGBDBM22359(1,3-Diarylprop-2-yn-1-one, 13p | methyl 4-[3-(4-me...)
Affinity DataIC50:  540nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed