BDBM223712 5-(6-{[(1r)-1- cyclobutylethyl]amino}- 8- (hexahydrocyclopenta [b][1,4]oxazin- 4(4ah)-yl)-7-[(trans- 4- methylcyclohexyl) methyl]-7h-purin-2- yl)-1,3,4-oxadiazol- 2(3h)-one (diastereomer 1)::US9540377, 11.140::US9540377, 11.141
SMILES C[C@@H](Nc1nc(nc2nc(N3CCOC4CCCC34)n(C[C@H]3CC[C@H](C)CC3)c12)-c1n[nH]c(=O)o1)C1CCC1
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 223712
Affinity DataIC50: 0.841nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair
Affinity DataIC50: 9.87nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair