BDBM223714 3-(6-{[(1r)-1- cyclobutylethyl]amino}- 7-[(trans-4- methylcyclohexyl) methyl]-8-[(3r)-3- pyridin-2- ylmorpholin-4-yl]- 7h-purin-2-yl)- 1,2,4-oxadiazol- 5(4h)-one::US9540377, 11.142
SMILES C[C@@H](Nc1nc(nc2nc(N3CCOC[C@H]3c3ccccn3)n(C[C@H]3CC[C@H](C)CC3)c12)-c1noc(=O)[nH]1)C1CCC1
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 223714
Affinity DataIC50: 0.774nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair