BDBM224018 (+)-TAN-67

SMILES CN1CC[C@]2(Cc3nc4ccccc4cc3C[C@@H]2C1)c1cccc(O)c1

InChI Key InChIKey=LEPBHAAYNPPRRA-XXBNENTESA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224018   

TargetMas-related G-protein coupled receptor member X2(Homo sapiens (Human))
University of North Carolina

LigandPNGBDBM224018((+)-TAN-67)
Affinity DataEC50:  290nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM224018((+)-TAN-67)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human DOR expressed in CHO cells assessed as reduction in ERK1/2 phosphorylation levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMas-related G-protein coupled receptor member X2(Homo sapiens (Human))
University of North Carolina

LigandPNGBDBM224018((+)-TAN-67)
Affinity DataEC50:  430nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed