BDBM224103 6-(3-chlorophenyl)-7- [(trans-4- methylcyclohexyl) methyl]-8-[(3r)-3- phenylmorpholin-4- yl]-7h-purine-2- carboxylic acid::US9540377, 16.22
SMILES C[C@H]1CC[C@H](Cn2c(nc3nc(nc(-c4cccc(Cl)c4)c23)C(O)=O)N2CCOC[C@H]2c2ccccc2)CC1
InChI Key InChIKey=VWJDPKRHKJMTOW-SKPFHBQLSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 224103
Affinity DataIC50: 0.680nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair