BDBM224640 US9328111, 13

SMILES CC(C)(C)OC(=O)N1CCc2c(C1)[nH]c1cccc3c1c2n[nH]c3=O

InChI Key InChIKey=RDWMOYFDWSZBAZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 224640   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM224640(US9328111, 13)
Affinity DataIC50:  5.10nMpH: 8.0Assay Description:PARP1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP1 was pre-incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM224640(US9328111, 13)
Affinity DataIC50:  7nMAssay Description:Tankyrase-2 enzymatic assay was conducted using commercial Tankyrase-2 Chemiluminescent Assay Kit (BPS Biosciences) and the protocol with the kit. GS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM224640(US9328111, 13)
Affinity DataIC50:  270nMAssay Description:PARP2 and PARP3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM224640(US9328111, 13)
Affinity DataIC50:  0.5nMAssay Description:PARP2 and PARP3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent