BDBM225895 MAP14::US9592235, Example 192::US9855269, Compound 38

SMILES CN(C)CCC(=O)Nc1cc(F)cc(c1)-c1ccc2ncnc(N)c2c1

InChI Key InChIKey=RSASMEONNPBNKR-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 225895   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225895(MAP14 | US9592235, Example 192 | US9855269, Compou...)
Affinity DataKi:  75.5nM IC50:  88.4nMAssay Description:Z'Lyte AssayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225895(MAP14 | US9592235, Example 192 | US9855269, Compou...)
Affinity DataIC50:  88.4nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225895(MAP14 | US9592235, Example 192 | US9855269, Compou...)
Affinity DataIC50:  88.4nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent