BDBM225901 MAP19::US9855269, Compound 342

SMILES Cc1c[nH]nc1-c1cccc(c1)-c1ccc2ncnc(N)c2n1

InChI Key InChIKey=COKPJYACYSCAQR-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 225901   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225901(MAP19 | US9855269, Compound 342)
Affinity DataKi:  3.66nM IC50:  3.11nMAssay Description:Z'Lyte AssayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225901(MAP19 | US9855269, Compound 342)
Affinity DataIC50:  3.11nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent