BDBM22782 2,3,5,6-tetrachlorocyclohexa-2,5-diene-1,4-dione::Benzil-related compound, 56::Benzil-related compound, 57::acs.jmedchem.1c00409_ST.350

SMILES ClC1=C(Cl)C(=O)C(Cl)=C(Cl)C1=O

InChI Key InChIKey=UGNWTBMOAKPKBL-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 22782   

TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
University of Mississippi

LigandPNGBDBM22782(2,3,5,6-tetrachlorocyclohexa-2,5-diene-1,4-dione |...)
Affinity DataKi:  54.8nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22782(2,3,5,6-tetrachlorocyclohexa-2,5-diene-1,4-dione |...)
Affinity DataKi:  57.4nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22782(2,3,5,6-tetrachlorocyclohexa-2,5-diene-1,4-dione |...)
Affinity DataKi:  83.9nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22782(2,3,5,6-tetrachlorocyclohexa-2,5-diene-1,4-dione |...)
Affinity DataKi:  163nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Mississippi

LigandPNGBDBM22782(2,3,5,6-tetrachlorocyclohexa-2,5-diene-1,4-dione |...)
Affinity DataKi:  268nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM22782(2,3,5,6-tetrachlorocyclohexa-2,5-diene-1,4-dione |...)
Affinity DataIC50:  4.10E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed