BDBM230172 US9340500, I-016
SMILES Cc1c(cc(-c2ccccc2)n1CCCN(CCO)CCO)C(=O)Nc1cccc(c1)C(F)(F)F
InChI Key InChIKey=AZSGJTXCLLMVJY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 230172
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 191nM ΔG°: -9.53kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataIC50: 130nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair