BDBM230179 US9340500, I-023
SMILES Cc1c(cc(-c2ccccc2)n1CCCN)C(=O)Nc1cccc(c1)C(F)(F)F
InChI Key InChIKey=HYAWDPIBZKQKMA-UHFFFAOYSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 230179
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 605nM ΔG°: -8.82kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair