BDBM230222 US9340500, I-066

SMILES CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)c1cnc2ccccc2n1

InChI Key InChIKey=HRTXEOCBPQVOLO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230222   

TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM230222(US9340500, I-066)
Affinity DataKi:  662nM ΔG°:  -8.76kcal/moleT: 2°CAssay Description:Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent