BDBM230241 US9340500, I-085

SMILES FC(F)(F)c1cccc(NC(=O)c2cc(nn2CCCN2CCOCC2)-c2ccccc2)c1

InChI Key InChIKey=JVGCUQBVYXBRCP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230241   

TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM230241(US9340500, I-085)
Affinity DataKi:  590nM ΔG°:  -8.83kcal/mole IC50:  1.30E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent