BDBM230247 US9340500, I-091
SMILES Cc1c(cc(n1CCC(=O)N1CCOCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F
InChI Key InChIKey=VDTIJADGSDUURJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 230247
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi
US Patent
Shionogi
US Patent
Affinity DataKi: 560nM ΔG°: -8.87kcal/mole IC50: 1.50E+3nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair