BDBM230256 US9340500, I-100

SMILES CNCC(C)(C)Cn1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=WKGSQJISFMHNTF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 230256   

TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM230256(US9340500, I-100)
Affinity DataKi:  290nM ΔG°:  -9.27kcal/mole IC50:  830nMT: 2°CAssay Description:Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent