BDBM231660 DMe (11)::US10668094, Compound DMe
SMILES C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(C)CC(C)O2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1
InChI Key InChIKey=IJOBTPPMUDSRAS-NVAUYEMTSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 231660
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Homo sapiens (Human))
Yeda Research and Development
US Patent
Yeda Research and Development
US Patent
Affinity DataKi: 10.8nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research and Development
US Patent
Yeda Research and Development
US Patent
Affinity DataKi: 15.3nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Homo sapiens (Human))
Yeda Research and Development
US Patent
Yeda Research and Development
US Patent
Affinity DataKi: 15.6nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-2(Homo sapiens (Human))
Yeda Research and Development
US Patent
Yeda Research and Development
US Patent
Affinity DataKi: 20.4nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Homo sapiens (Human))
Weizmann Institute of Science
Weizmann Institute of Science
Affinity DataKi: 101nMAssay Description:Inhibition of Na,K-ATPase activity of the detergent-soluble α1β1, α2β1, and α3β1 complexes by CGs was done exactly as d...More data for this Ligand-Target Pair
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Homo sapiens (Human))
Weizmann Institute of Science
Weizmann Institute of Science
Affinity DataKi: 103nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair