BDBM232930 US9346839, 11::US9738668, Compound 11

SMILES COc1ccc2nc(N[C@@H](c3ccc[nH]3)P(=O)(OC)OC)sc2c1

InChI Key

Data  2 KI  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 232930   

TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM232930(US9346839, 11 | US9738668, Compound 11)
Affinity DataKi:  9.60E+3nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-hydroxyacyl-CoA dehydrogenase type-2(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM232930(US9346839, 11 | US9738668, Compound 11)
Affinity DataKi:  9.60E+3nM ΔG°:  -6.84kcal/mole IC50:  3.41E+4nM Kd:  380nMpH: 7.3 T: 2°CAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM232930(US9346839, 11 | US9738668, Compound 11)
Affinity DataKd:  380nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM232930(US9346839, 11 | US9738668, Compound 11)
Affinity DataIC50:  3.41E+4nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent