BDBM23446 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one::CHEMBL45068::Phloretin::cid_4788
SMILES Oc1ccc(CCC(=O)c2c(O)cc(O)cc2O)cc1
InChI Key InChIKey=VGEREEWJJVICBM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 23446
TargetSolute carrier family 28 member 3(Homo sapiens (Human))
University Of Tennessee Health Sciences Center
Curated by ChEMBL
University Of Tennessee Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 3.23E+4nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Max-Planck-Institut F£R Molekulare Physiologie
Curated by ChEMBL
Max-Planck-Institut F£R Molekulare Physiologie
Curated by ChEMBL
Affinity DataKi: 8.60E+4nMAssay Description:Binding affinity against Sodium/glucose co-transporter of isolated renal brush border membranes.More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 6 hits for monomerid = 23446
ITC DataΔG°: -10.2kcal/mole −TΔS°: 4.89kcal/mole ΔH°: -15.1kcal/mole logk: 2.10E+7
pH: 7.0 T: 30.00°C
pH: 7.0 T: 30.00°C
ITC DataΔG°: -8.29kcal/mole −TΔS°: 8.70kcal/mole ΔH°: -17.0kcal/mole logk: 9.75E+5
pH: 7.0 T: 30.00°C
pH: 7.0 T: 30.00°C
ITC DataΔG°: -6.99kcal/mole −TΔS°: 14.6kcal/mole ΔH°: -21.6kcal/mole logk: 1.09E+5
pH: 7.0 T: 30.00°C
pH: 7.0 T: 30.00°C
ITC DataΔG°: -8.25kcal/mole −TΔS°: 7.43kcal/mole ΔH°: -15.7kcal/mole logk: 9.00E+5
pH: 7.0 T: 30.00°C
pH: 7.0 T: 30.00°C
ITC DataΔG°: -8.74kcal/mole −TΔS°: 10.4kcal/mole ΔH°: -19.2kcal/mole logk: 2.05E+6
pH: 7.0 T: 30.00°C
pH: 7.0 T: 30.00°C
ITC DataΔG°: -6.87kcal/mole −TΔS°: -4.88kcal/mole ΔH°: -1.99kcal/mole logk: 9.14E+4
pH: 7.0 T: 30.00°C
pH: 7.0 T: 30.00°C