BDBM23463 hydroxamate deriv., 55::methyl (1R,2R)-2-(hydroxycarbamoyl)-1-(3-{[3-(trifluoromethyl)phenyl]methoxy}phenyl)cyclopropane-1-carboxylate

SMILES COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2cccc(c2)C(F)(F)F)c1

InChI Key InChIKey=HFBCDWUJKHOSLS-LPHOPBHVSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23463   

TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM23463(hydroxamate deriv., 55 | methyl (1R,2R)-2-(hydroxy...)
Affinity DataKi:  70nM ΔG°:  -9.66kcal/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed