BDBM23469 hydroxamate deriv., 61::methyl (1R,2R)-2-(hydroxycarbamoyl)-1-{3-[2-(naphthalen-2-yl)ethoxy]phenyl}cyclopropane-1-carboxylate

SMILES COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCCc2ccc3ccccc3c2)c1

InChI Key InChIKey=WIUQVVMGJZANSX-URXFXBBRSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23469   

TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM23469(hydroxamate deriv., 61 | methyl (1R,2R)-2-(hydroxy...)
Affinity DataKi:  60nM ΔG°:  -9.75kcal/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed