BDBM235170 US9359348, 4
SMILES Cc1nc(C)n(n1)-c1cc(nc(C)n1)[C@@H]1C[C@H]1c1cn2ccc(C)cc2n1
InChI Key InChIKey=WPILBAXGXZASJB-HZPDHXFCSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 235170
TargetIsoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A2)(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 44nM ΔG°: -10.0kcal/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP FP kit supplied by Molecular Devices, Sunnyv...More data for this Ligand-Target Pair