BDBM235177 US9359348, 11
SMILES Cc1nc(C)n(n1)-c1cc(nc(C)n1)[C@@H]1C[C@H]1c1nc2ccccn2c1C#N
InChI Key InChIKey=OYUQKJXOYYQVTM-HUUCEWRRSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 235177
TargetIsoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A2)(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: >75nM ΔG°: >-9.71kcal/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP FP kit supplied by Molecular Devices, Sunnyv...More data for this Ligand-Target Pair