BDBM235765 US9359371, 50
SMILES COc1ccc(CNc2nc(ncc2C(=O)N[C@H]2CC[C@H](O)CC2)N2CC3CC3C2)cc1C
InChI Key InChIKey=IEZYPHZUBOUHML-FOUKWCRFSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 235765
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Xuanzhu Pharma
US Patent
Xuanzhu Pharma
US Patent
Affinity DataIC50: 660nMpH: 7.5Assay Description:Method: The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (0.2 μg/mL) in Tris-HCl buffer of pH 7.5. 100 μ...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Homo sapiens (Human))
Xuanzhu Pharma
US Patent
Xuanzhu Pharma
US Patent
Affinity DataIC50: 7.72nMpH: 7.5Assay Description:The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (35 μg/mL) in Tris-HCl buffer of pH 7.5. 1 μM cGMP and...More data for this Ligand-Target Pair