BDBM235961 US9365546, 284
SMILES Cc1cnc(cc1-n1c(C)cc(OCc2ccc(F)cc2F)c(Cl)c1=O)-c1ccnc(n1)C(C)(C)O
InChI Key InChIKey=WJYGDQYYYZYICM-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 235961
Target5-hydroxytryptamine receptor 2A/MAP kinase-activated protein kinase 2(Homo sapiens (Human))
Confluence Life Sciences
US Patent
Confluence Life Sciences
US Patent
Affinity DataIC50: 6.40nMpH: 7.5 T: 2°CAssay Description:Kinase reactions is carried out in a 384-well plate (Matrical, MP101-1-PP) in 20 mM HEPES pH 7.5, 10 mM MgCl2, 0.0005% Tween-20, 0.01% BSA, 1 mM DTT,...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/MAP kinase-activated protein kinase 2(Homo sapiens (Human))
Confluence Life Sciences
US Patent
Confluence Life Sciences
US Patent
Affinity DataIC50: 144nMpH: 7.5 T: 2°CAssay Description:Kinase reactions is carried out in a 384-well plate (Matrical, MP101-1-PP) in 20 mM HEPES pH 7.5, 10 mM MgCl2, 0.0005% Tween-20, 0.01% BSA, 1 mM DTT,...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/MAP kinase-activated protein kinase 2(Homo sapiens (Human))
Confluence Life Sciences
US Patent
Confluence Life Sciences
US Patent
Affinity DataIC50: 138nMpH: 7.5 T: 2°CAssay Description:Kinase reactions is carried out in a 384-well plate (Matrical, MP101-1-PP) in 20 mM HEPES pH 7.5, 10 mM MgCl2, 0.0005% Tween-20, 0.01% BSA, 1 mM DTT,...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A/MAP kinase-activated protein kinase 2(Homo sapiens (Human))
Confluence Life Sciences
US Patent
Confluence Life Sciences
US Patent
Affinity DataIC50: 7.30nMpH: 7.5 T: 2°CAssay Description:Kinase reactions is carried out in a 384-well plate (Matrical, MP101-1-PP) in 20 mM HEPES pH 7.5, 10 mM MgCl2, 0.0005% Tween-20, 0.01% BSA, 1 mM DTT,...More data for this Ligand-Target Pair